Mouse Neuregulin-3/NRG3 EGF-like Domain Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # BAF753

R&D Systems, part of Bio-Techne
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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG

View all Neuregulin-3/NRG3 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Neuregulin‑3/NRG3
Glu284-Pro344
Accession # O35181

Specificity

Detects mouse Neuregulin‑3/NRG3 EGF-like Domain in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse Neuregulin-3/NRG3 EGF-like Domain Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse Neuregulin-3/NRG3 EGF-like Domain

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Neuregulin-3/NRG3

The neuregulin (also known as heregulin) cytokine family is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. The NRG1 gene is the most pleiotropic, encoding more than 14 soluble or transmembrane proteins. NRG1 isoforms can be classified into type I (neu differentiation factor, NDF; heregulin, HRG; acetylcholine receptor inducing activity, ARIA), type II (glial growth factor, GGF) and type III (sensory and motor neuron-derived factor, SMDF) isoforms. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.

Alternate Names

Neuregulin3, NRG3

Entrez Gene IDs

10718 (Human); 18183 (Mouse)

Gene Symbol

NRG3

UniProt

O35181

Additional Neuregulin-3/NRG3 Products

Product Documents for Mouse Neuregulin-3/NRG3 EGF-like Domain Biotinylated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse Neuregulin-3/NRG3 EGF-like Domain Biotinylated Antibody

For research use only

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