MRP1 Antibody (QCRL) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # FAB19291B

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

MAB19291

Alexa Fluor 532

FAB19291X

Allophycocyanin

FAB19291A

CoraFluor 1

FAB19291CL1

DyLight 350

FAB19291D

DyLight 405

FAB19291E

DyLight 488

FAB19291K

DyLight 550

FAB19291L

DyLight 594

FAB19291M

DyLight 650

FAB19291W

DyLight 680

FAB19291Y

DyLight 755

FAB19291Z

FITC

FAB19291F

HRP

FAB19291H

Janelia Fluor 525

FAB19291JF525

Janelia Fluor 549

FAB19291I

Janelia Fluor 646

FAB19291J

Janelia Fluor 669

FAB19291JF669

mFluor Violet 450 SE

FAB19291MFV450

mFluor Violet 500 SE

FAB19291MFV500

mFluor Violet 610 SE

FAB19291MFV610

PerCP

FAB19291C

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Immunocytochemistry, Immunoprecipitation, Intracellular Staining by Flow Cytometry, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₁ Clone # QCRL

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MRP1 Antibodies »

Product Specifications

Immunogen

H69AR human small cell lung cancer cell line membrane extracts

Specificity

Detects human MRP1 in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for MRP1 Antibody (QCRL) [Biotin]

Application

Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Intracellular Staining by Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MRP1

Multidrug Resistance Protein 1 (MRP1) is an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein. MRP1 is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.

Specifically, MRP1 mediates the export of organic anions and drugs from the cytoplasm. It is through this function, that MRP1 is able to confer resistance to anticancer drugs. MRP1 antibodies are therefore useful tools for cancer testing and research.

Long Name

Multi-drug Resistance Protein 1

Alternate Names

ABCC1, GS-X

Gene Symbol

ABCC1

Additional MRP1 Products

Product Documents for MRP1 Antibody (QCRL) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MRP1 Antibody (QCRL) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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