MYCBP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-68745

Novus Biologicals, part of Bio-Techne
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NBP2-68745
NBP2-68745-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MYCBP2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: CYHPAKPFQSQLPSVKEGISEDLPVKMPCLYLQTLARHHHENFVGYQDDNLFQDEMRYLRSTSVPAPYISVTPDASPNVFEEPESNMKSMPPSL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MYCBP2 Antibody

Immunocytochemistry/ Immunofluorescence: MYCBP2 Antibody [NBP2-68745]

Immunocytochemistry/ Immunofluorescence: MYCBP2 Antibody [NBP2-68745]

Immunocytochemistry/Immunofluorescence: MYCBP2 Antibody [NBP2-68745] - Staining of human cell line U-2 OS shows localization to nucleus & vesicles.

Applications for MYCBP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Recommended conditions: Fixation/Permeabilization: PFA/Triton X-100

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MYCBP2

In addition to its possible functions as a facilitator of Myc activated transcription, PAM (protein associated with Myc) has also been shown to play a role in mTOR signaling. PAM functions as an E3 ubiquitin ligase for tuberin (TSC2), a negative regulator of the mTOR pathway. Additionally PAM has been shown to function as a guanosine exchange factor (GEF) for Rheb and to facilitate sphingosine-1-phosphate signaling in the mTOR pathway. Alternative names for PAM include Myc-binding protein 2, MYCBP2, Pam/highwire/rpm-1 protein, and KIAA0916.

Alternate Names

DKFZp686M08244, EC 6.3.2.-, FLJ10106, FLJ21646, KIAA0916FLJ13826, MYC binding protein 2, Myc-binding protein 2, Pam/highwire/rpm-1 protein, PAMFLJ21597, probable E3 ubiquitin-protein ligase MYCBP2, Protein associated with Myc

Gene Symbol

MYCBP2

Additional MYCBP2 Products

Product Documents for MYCBP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MYCBP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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