NF-H Antibody (RT-97 + NR-4) - Azide and BSA Free

Validated:

Unconjugated

Monoclonal Mouse IgG1 Kappa/IgG1 Kappa Clone # RT-97 + NR-4

Azide and BSA Free

1.0 mg/ml

Triton-X 100 insoluble proteins of rat brain (RT-97); Neurofilaments from porcine spinal cord (NR-4) (Uniprot: P12036)

Cytoplasmic

This monoclonal antibody reacts with a 200kDa and 68kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Neuronal Marker

Monoclonal

Mouse

IgG1 Kappa/IgG1 Kappa

1.0 mg/ml of antibody purified from Bioreactor Concentrate. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP2-45280).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Protein G purified

10 mM PBS

Azide and BSA Free

No Preservative

1.0 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at -20 to -80C. Avoid freeze-thaw cycles.