NGFR/TNFRSF16/p75NTR Antibody (NTR/912) [Biotin]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47966B
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Mouse (Negative), Primate, Rat (Negative)
Applications
CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Biotin
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # NTR/912
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for NGFR/TNFRSF16/p75NTR Antibody (NTR/912) [Biotin]
Immunogen
Recombinant human NGFR/TNFRSF16/p75NTR protein (Uniprot: P08138)
Reactivity Notes
Non-Human primates. Does not react with Mouse or Rat.
Localization
Cell surface and cytoplasmic
Specificity
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Marker
Soft Tissue Tumor Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Applications for NGFR/TNFRSF16/p75NTR Antibody (NTR/912) [Biotin]
Application
Recommended Usage
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: NGFR/TNFRSF16
Long Name
Nerve Growth Factor Receptor
Alternate Names
CD271, NGF R, p75 NTR, TNFRSF16
Gene Symbol
NGFR
Additional NGFR/TNFRSF16 Products
Product Documents for NGFR/TNFRSF16/p75NTR Antibody (NTR/912) [Biotin]
Product Specific Notices for NGFR/TNFRSF16/p75NTR Antibody (NTR/912) [Biotin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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