NIK/MAP3K14 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83414

Novus Biologicals, part of Bio-Techne
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NBP1-83414
NBP1-83414-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NIK/MAP3K14 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids:SVYKLEAVEKSPVFCGKWEILNDVITKGTAKEGSEAGPAAISIIAQAECENSQEFSPTFSERIFIAGSKQYSQSESLDQIPNNVAHA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NIK/MAP3K14 Antibody

Western Blot: NIK/MAP3K14 Antibody [NBP1-83414]

Western Blot: NIK/MAP3K14 Antibody [NBP1-83414]

Western Blot: NIK/MAP3K14 Antibody [NBP1-83414] - Analysis in control (vector only transfected HEK293T lysate) and MAP3K14 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414]

Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414]

Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414] - Staining of human liver shows negative to very weak positivity in hepatocytes.
Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414]

Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414]

Immunohistochemistry-Paraffin: NIK/MAP3K14 Antibody [NBP1-83414] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells.
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Applications for NIK/MAP3K14 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NIK/MAP3K14

MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14) kinase binds to TRAF2 and stimulates NF-kappaB activity. MAP3K14 is regulated by MAP3K7, RIPK1, TRAF2, TRAF6 and TRAF3. MAP3K14 has been studied in relation to salivary gland cancer, rheumatoid arthritis, t-cell leukemia, ectodermal dysplasia, melanoma and several other diseases and disorders.

Long Name

NF-kappa-beta Inducing Kinase

Alternate Names

FTDCR1B, HSNIK, MAP3K14

Gene Symbol

MAP3K14

Additional NIK/MAP3K14 Products

Product Documents for NIK/MAP3K14 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NIK/MAP3K14 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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