NMDAR2C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10352

Novus Biologicals, part of Bio-Techne
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NBP3-10352-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all GRIN2C/NMDAR2C Antibodies »

Product Summary for NMDAR2C Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NMDAR2C (NP_000826). Peptide sequence VNTTNPSSLLTQICGLLGAAHVHGIVFEDNVDTEAVAQILDFISSQTHVP

Specificity

Epsilon-3 subunit

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

136 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NMDAR2C Antibody

Immunohistochemistry-Paraffin: NMDAR2C Antibody [NBP3-10352]

Immunohistochemistry-Paraffin: NMDAR2C Antibody [NBP3-10352]

Immunohistochemistry-Paraffin: NMDAR2C Antibody [NBP3-10352] - Immunohistochemical analysis of formalin-fixed paraffin-embedded human adult heart tissue.

Applications for NMDAR2C Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GRIN2C/NMDAR2C

The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are also implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors also appear to be a target for ethanol at physiological concentrations and therefore may play a significant role in alcoholism.

Long Name

Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate, Subunit 2C

Alternate Names

NMDA R, NR2C Subunit, NMDAR2C, NR2C

Gene Symbol

GRIN2C

Additional GRIN2C/NMDAR2C Products

Product Documents for NMDAR2C Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NMDAR2C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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