GRIN2C/NMDAR2C Products
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.
Products:
24 results for "GRIN2C/NMDAR2C" in Products
24 results for "GRIN2C/NMDAR2C" in Products
GRIN2C/NMDAR2C Products
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.
Products:
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, IP, Simple Western |
Reactivity: | Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit Polyclonal |
Applications: | IHC, WB |
Applications: | WB, ELISA, MA, AP |
Reactivity: | Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Applications: | WB |
Applications: | ELISA |
Applications: | ELISA |
Non-competitive NMDA antagonist; acts at ion channel site
Alternate Names: | Dizocilpine |
Chemical Name: | (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate |
Purity: | ≥99% (HPLC) |
Broad spectrum glutamatergic antagonist
Chemical Name: | 4-Hydroxyquinoline-2-carboxylic acid |
Purity: | ≥98% (HPLC) |
NMDA antagonist; antidepressant; may not display psychotomimetic or addictive side effects of (S)-ketamine
Chemical Name: | (R)-(-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride |
Purity: | ≥99% (HPLC) |
Positive allosteric modulator of NMDA receptors; acts in transmembrane domain
Chemical Name: | 4-Cyclohexyl-N-(7-hydroxy-5-methyl-2-propyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)benzenesulfonamide |
Purity: | ≥98% (HPLC) |
Potentiator of NMDA receptors containing GluN2C/GluN2D
Chemical Name: | (3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone |
Purity: | ≥98% (HPLC) |
Potent NMDA antagonist; acts at glycine site
Chemical Name: | 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid |
Purity: | ≥98% (HPLC) |
Specific σ ligand, NMDA antagonist
Chemical Name: | 4-Phenyl-1-(4-phenylbutyl)piperidine maleate |
Purity: | ≥99% (HPLC) |
Highly potent NMDA antagonist
Chemical Name: | trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline |
Purity: | ≥99% (HPLC) |
GluN2C/GluN2D-selective NMDA antagonist
Chemical Name: | 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid |
Purity: | ≥97% (HPLC) |
Non-competitive and GluN2C/GluN2D-selective NMDA antagonist
Chemical Name: | 4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)quinazolinyl]benzoic acid |
Purity: | ≥98% (HPLC) |
Potent and selective NMDA antagonist; acts at the glycine site
Alternate Names: | GV 150526A |
Chemical Name: | 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt |
Purity: | ≥98% (HPLC) |
Potent and selective NMDA antagonist
Chemical Name: | (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid |
Purity: | ≥99% (HPLC) |
GluN2C/GluN2D-selective NMDA antagonist
Chemical Name: | (2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid |
Purity: | ≥98% (HPLC) |
NMDA antagonist; acts at glycine site
Chemical Name: | 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone |
Purity: | ≥99% (HPLC) |
Potent and noncompetitive NMDA antagonist
Alternate Names: | CNS 1102 |
Chemical Name: | N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride |
Purity: | ≥98% (HPLC) |