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GRIN2C/NMDAR2C Products

NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.

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24 results for "GRIN2C/NMDAR2C" in Products

24 results for "GRIN2C/NMDAR2C" in Products

GRIN2C/NMDAR2C Products

NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity. NMDARs are heteromeric complexes of multiple subunits: NR1, which occurs as eight distinct isoforms as the result of alternate splicing; NR2 (NR2A, B, C and D are encoded by four related genes, several of which also display multiple splice forms); and NR3 (NR3A and B also have several splice forms). The particular combination of subunits determines the functional characteristics of the receptor.

Products:

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Applications: WB, IP
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ICC/IF, IP, Simple Western
Reactivity: Human, Mouse, Rat
Applications: WB
Reactivity: Mouse, Rat
Applications: IHC, WB
Reactivity: Human
Applications: WB, ELISA, MA, AP
Applications: WB
Reactivity: Mouse, Rat
Applications: WB
Applications: ELISA
Applications: ELISA

Non-competitive NMDA antagonist; acts at ion channel site

Broad spectrum glutamatergic antagonist

NMDA antagonist; antidepressant; may not display psychotomimetic or addictive side effects of (S)-ketamine

Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

Potentiator of NMDA receptors containing GluN2C/GluN2D

Potent NMDA antagonist; acts at glycine site

Specific σ ligand, NMDA antagonist

Highly potent NMDA antagonist

GluN2C/GluN2D-selective NMDA antagonist

Non-competitive and GluN2C/GluN2D-selective NMDA antagonist

Potent and selective NMDA antagonist; acts at the glycine site

Potent and selective NMDA antagonist

GluN2C/GluN2D-selective NMDA antagonist

NMDA antagonist; acts at glycine site

Potent and noncompetitive NMDA antagonist

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