PDE4B Antibody (OTI1D12) [mFluor Violet 610 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-73292MFV610

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-01171

Alexa Fluor 350

NBP2-73292AF350

Alexa Fluor 405

NBP2-73292AF405

Alexa Fluor 488

NBP2-73292AF488

Alexa Fluor 532

NBP2-73292AF532

Alexa Fluor 594

NBP2-73292AF594

Alexa Fluor 647

NBP2-73292AF647

Alexa Fluor 700

NBP2-73292AF700

Alexa Fluor 750

NBP2-73292AF750

Allophycocyanin

NBP2-73292APC

Allophycocyanin/Cy7

NBP2-73292APCCY7

Biotin

NBP2-73292B

CoraFluor 1

NBP2-73292CL1

DyLight 350

NBP2-73292UV

DyLight 405

NBP2-73292V

DyLight 488

NBP2-73292G

DyLight 550

NBP2-73292R

DyLight 594

NBP2-73292DL594

DyLight 650

NBP2-73292C

DyLight 680

NBP2-73292FR

DyLight 755

NBP2-73292IR

FITC

NBP2-73292F

HRP

NBP2-73292H

Janelia Fluor 525

NBP2-73292JF525

Janelia Fluor 549

NBP2-73292JF549

Janelia Fluor 585

NBP2-73292JF585

Janelia Fluor 635

NBP2-73292JF635

Janelia Fluor 646

NBP2-73292JF646

Janelia Fluor 669

NBP2-73292JF669

mFluor Violet 450 SE

NBP2-73292MFV450

mFluor Violet 500 SE

NBP2-73292MFV500

PE

NBP2-73292PE

PE/Atto594

NBP2-73292PEATT594

PE/Cy5.5

NBP2-73292PECY55

PE/Cy7

NBP2-73292PECY7

PerCP

NBP2-73292PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-73292

Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

mFluor Violet 610 SE (Excitation = 421 nm, Emission = 613 nm)

Antibody Source

Monoclonal Mouse IgG₁ Clone # OTI1D12

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PDE4B Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Scientific Data Images for PDE4B Antibody (OTI1D12) [mFluor Violet 610 SE]

PDE4B Antibody (OTI1D12) [mFluor Violet 610 SE] [NBP2-73292MFV610] -

PDE4B Antibody (OTI1D12) [mFluor Violet 610 SE] [NBP2-73292MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.

Applications for PDE4B Antibody (OTI1D12) [mFluor Violet 610 SE]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PDE4B

PDE4B is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Enzymes of the cAMP-dependent phosphodiesterase type 4 (PDE4) family are important in hydrolyzing cAMP produced by G-protein coupled receptor (GPCR) stimulated adenylyl cyclases. Four genes (PDE4A, B, C and D) make up the PDE4 family. cAMP-dependent phosphodiesterase type B (PDE4B) family consists of four known splice variants, PDE4B1, B2, B3 and a novel 66 kDa PDE4B4 protein. One or more subtype variants of PDE4B are ubiquitously present in all mammalian cells. In CNS, all four PDE4B subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation. Some PDE4B variants are also substrate for PKA-dependent phosphorylation. Peripheral tissues exhibit differential expression of PDE4B1, B2 and B4 variants; the PDE4B4 (66kDa protein) is the major PDE4B variant expressed in lungs, testis and heart. In testis PDE4B enzymes are expressed in somatic cells (Sertoli and Leydig cells) while PDE4A is localized in germ cells.

Long Name

cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Alternate Names

DPDE4, PDE32

Gene Symbol

PDE4B

Additional PDE4B Products

Product Documents for PDE4B Antibody (OTI1D12) [mFluor Violet 610 SE]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PDE4B Antibody (OTI1D12) [mFluor Violet 610 SE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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