PDGF R beta Antibody (18A2) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-47232

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 18A2

Format

BSA Free

Concentration

1 mg/ml

View all PDGF R beta Antibodies »

Product Summary for PDGF R beta Antibody (18A2) - BSA Free

Immunogen

CD140b-transfected NIH 3T3 cells

Specificity

The monoclonal antibody 18A2 recognizes CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

190 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PDGF R beta Antibody (18A2) - BSA Free

Flow Cytometry: PDGF R beta Antibody (18A2) - BSA Free [NBP1-47232]

Flow Cytometry: PDGF R beta Antibody (18A2) - BSA Free [NBP1-47232]

Flow Cytometry: PDGF R beta Antibody (18A2) [NBP1-47232] - Human CD140b / PDGF-RB stable transfectants with anti-CD140b (18A2) APC.
Flow Cytometry: PDGF R beta Antibody (18A2) - BSA Free [NBP1-47232]

Flow Cytometry: PDGF R beta Antibody (18A2) - BSA Free [NBP1-47232]

Flow Cytometry: PDGF R beta Antibody (18A2) [NBP1-47232] - Human CD140b / PDGF-RB stable transfectants with anti-CD140b (18A2) purified GAM-APC.

Applications for PDGF R beta Antibody (18A2) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Immunocytochemistry/ Immunofluorescence

1:10-1:2000
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Format

BSA Free

Preservative

0.9% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: PDGF R beta

CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.

Long Name

Platelet-derived Growth Factor Receptor beta

Alternate Names

CD140b, PDGFRB

Gene Symbol

PDGFRB

Additional PDGF R beta Products

Product Documents for PDGF R beta Antibody (18A2) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PDGF R beta Antibody (18A2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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