PDGF R beta Antibody (RM0005-4C54) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-61021

Novus Biologicals, part of Bio-Techne
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NB110-61021-0.025mg
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2 Clone # RM0005-4C54

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all PDGF R beta Antibodies »

Product Summary for PDGF R beta Antibody (RM0005-4C54) - Azide and BSA Free

Immunogen

Mouse PDGF R beta (extracellular domain)

Clonality

Monoclonal

Host

Rat

Isotype

IgG2

Scientific Data Images for PDGF R beta Antibody (RM0005-4C54) - Azide and BSA Free

Immunohistochemistry-Paraffin: PDGF R beta Antibody (RM0005-4C54) - Azide and BSA Free [NB110-61021]

Immunohistochemistry-Paraffin: PDGF R beta Antibody (RM0005-4C54) - Azide and BSA Free [NB110-61021]

Immunohistochemistry-Paraffin: PDGF R beta Antibody (RM0005-4C54) [NB110-61021] - Staining of paraffin sections of mouse pancreas from LPS exposed animals.

Applications for PDGF R beta Antibody (RM0005-4C54) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PDGF R beta

Platelet-derived growth factors (PDGFs) exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.

Long Name

Platelet-derived Growth Factor Receptor beta

Alternate Names

CD140b, PDGFRB

Entrez Gene IDs

18596 (Mouse)

Gene Symbol

PDGFRB

Additional PDGF R beta Products

Product Documents for PDGF R beta Antibody (RM0005-4C54) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PDGF R beta Antibody (RM0005-4C54) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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