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PMS2 Antibody (163C1251) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80914

Novus Biologicals, part of Bio-Techne
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NBP2-80914
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 163C1251

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Summary for PMS2 Antibody (163C1251) - Azide and BSA Free

Immunogen

This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 623-639 SSLAKRIKQLHHEAQQS of human PMS2; GenBank No. NP_000526.1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for PMS2 Antibody (163C1251) - Azide and BSA Free

Western Blot: PMS2 Antibody (163C1251)Azide and BSA Free [NBP2-80914]

Western Blot: PMS2 Antibody (163C1251)Azide and BSA Free [NBP2-80914]

Western Blot: PMS2 Antibody (163C1251) - Azide and BSA Free [NBP2-80914] - Analysis of PMS2 using this antibody at 2 ug/ml against 10 ug of NIH 3T3 cell lysate. Image from the standard format of this antibody.
Immunohistochemistry-Paraffin: PMS2 Antibody (163C1251) - Azide and BSA Free [NBP2-80914]

Immunohistochemistry-Paraffin: PMS2 Antibody (163C1251) - Azide and BSA Free [NBP2-80914]

Immunohistochemistry-Paraffin: PMS2 Antibody (163C1251) - Azide and BSA Free [NBP2-80914] - Analysis of formalin fixed paraffin-embedded (FFPE) human colon cancer using PMS2 antibody at 5 ug/ml on a Bond Rx autostainer (Leica Biosystems). The assay involved 20 minutes of heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH

Applications for PMS2 Antibody (163C1251) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1ug per 10^6 cells

Immunohistochemistry

2-5ug/ml

Immunohistochemistry-Paraffin

2-5ug/ml

Western Blot

1-2 ug/ml
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PMS2

PMS1 protein homologue 2 (PMS2) is a DNA mismatch repair protein. Defects in PMS2 are a cause of hereditary non-polyposis cancer (HNPCC). Human PMS2 is an amino acid protein of 862 amino acids.

Alternate Names

DNA mismatch repair protein PMS2, EC 3.1, H_DJ0042M02.9, HNPCC4postmeiotic segregation increased (S. cerevisiae) 2, mismatch repair endonuclease PMS2, PMS1 protein homolog 2, PMS2 postmeiotic segregation increased 2 (S. cerevisiae), PMSL2PMS2CL

Gene Symbol

PMS2

Additional PMS2 Products

Product Documents for PMS2 Antibody (163C1251) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PMS2 Antibody (163C1251) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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