Progesterone R/NR3C3 Antibody (Alpha PR6) [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # NB120-2765JF525

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB120-2765AF350

Alexa Fluor 405

NB120-2765AF405

Alexa Fluor 488

NB120-2765AF488

Alexa Fluor 532

NB120-2765AF532

Alexa Fluor 594

NB120-2765AF594

Alexa Fluor 647

NB120-2765AF647

Alexa Fluor 700

NB120-2765AF700

Alexa Fluor 750

NB120-2765AF750

Biotin

NB120-2765B

CoraFluor 1

NB120-2765CL1

DyLight 350

NB120-2765UV

DyLight 405

NB120-2765V

DyLight 488

NB120-2765G

DyLight 550

NB120-2765R

DyLight 594

NB120-2765DL594

DyLight 650

NB120-2765C

DyLight 680

NB120-2765FR

DyLight 755

NB120-2765IR

FITC

NB120-2765F

HRP

NB120-2765H

Janelia Fluor 549

NB120-2765JF549

Janelia Fluor 646

NB120-2765JF646

Janelia Fluor 669

NB120-2765JF669

mFluor Violet 450 SE

NB120-2765MFV450

mFluor Violet 500 SE

NB120-2765MFV500

mFluor Violet 610 SE

NB120-2765MFV610

Forumulation

Catalog #

BSA Free

NB120-2765

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat, Bovine, Chicken, Guinea Pig, Primate, Rabbit, Sheep

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Janelia Fluor 525

Antibody Source

Monoclonal Mouse IgG_2A Clone # Alpha PR6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Progesterone R/NR3C3 Antibodies »

Product Specifications

Immunogen

Progesterone receptor purified from chick oviduct cytosol.

Reactivity Notes

Primate reactivity reported in scientific literature (PMID: 18980817). Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Localization

Nuclear

Specificity

Detects the B form of the progesterone receptor (PR). This does not cross-react with estrogen receptor or glucocorticoid receptor.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Applications for Progesterone R/NR3C3 Antibody (Alpha PR6) [Janelia Fluor® 525]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Progesterone R/NR3C3

The human Progesterone Receptor (PgR) is a member of the steroid family of nuclear receptors. PgR is found as a 120 kDa protein (Form B) or a 94 kDa protein (Form A) due to the use of alternative translation initiation sites. In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins. Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription.

Long Name

Progesterone Receptor

Alternate Names

NR3C3, PGR, ProgesteroneR

Gene Symbol

PGR

Additional Progesterone R/NR3C3 Products

Product Documents for Progesterone R/NR3C3 Antibody (Alpha PR6) [Janelia Fluor® 525]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Progesterone R/NR3C3 Antibody (Alpha PR6) [Janelia Fluor® 525]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews