The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. (provided by RefSeq)

Alternate Names

26S proteasome regulatory subunit RPN3, 26S proteasome regulatory subunit S3, P58, proteasome (prosome, macropain) 26S subunit, non-ATPase, 3, Proteasome subunit p58, Rpn3, S3, 26S proteasome non-ATPase regulatory subunit 3, tissue specific transplantation antigen 2, TSTA2

Gene Symbol

PSMD3

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Product Specific Notices for Proteasome 19S S3 Antibody (OTI2A2) [DyLight 550]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Proteasome 19S S3 Antibody (OTI2A2) [DyLight 550]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-73636R

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Applications for Proteasome 19S S3 Antibody (OTI2A2) [DyLight 550]

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Background: Proteasome 19S S3

Alternate Names

Gene Symbol

Additional Proteasome 19S S3 Products

Product Documents for Proteasome 19S S3 Antibody (OTI2A2) [DyLight 550]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Proteasome 19S S3 Antibody (OTI2A2) [DyLight 550]

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