Rat Neurexin 1 beta/NXRN1b Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF4524
Key Product Details
Species Reactivity
Rat
Applications
Western Blot
Label
Biotin
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant rat Neurexin 1 beta isoform 1
Ala47-Thr392
Accession # Q63373
Ala47-Thr392
Accession # Q63373
Specificity
Detects rat Neurexin 1 beta in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant rat Neurexin 1 alpha is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Rat Neurexin 1 beta/NXRN1b Biotinylated Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Rat Neurexin 1 beta/NXRN1b
Sample: Recombinant Rat Neurexin 1 beta/NXRN1b
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Neurexin 1 beta/NXRN1b
Neurexin 1 beta is an 80 kDa member of the Neurexin family of proteins. It is expressed on neuronal presynaptic membranes and contributes to synapse formation through binding to postsynaptic neuroligins. An alternate start site in the Neurexin 1 gene generate an alpha- (long) and beta- (short) isoform. Mature rat Neurexin 1 beta is a type I transmembrane glycoprotein that is 468 amino acids (aa) in length. It has a 346 aa extracellular region (aa 47‑392) that contains one laminin-like G domain (aa 91‑264). Within the G domain, the presence or absence of a splice site (aa 201‑230) materially impacts neuroligin binding. Over aa 47‑392, rat Neurexin 1 beta is 100% and 98% aa identical to mouse and human Neurexin 1 beta, respectively.
Alternate Names
NXR1B, NXRN1b
Gene Symbol
NRXN1
UniProt
Additional Neurexin 1 beta/NXRN1b Products
Product Documents for Rat Neurexin 1 beta/NXRN1b Biotinylated Antibody
Product Specific Notices for Rat Neurexin 1 beta/NXRN1b Biotinylated Antibody
For research use only
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