ROR gamma/RORC/NR1F3 Antibody (RORC/8278R)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26721

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-26721-100ug
NBP3-26721-20ug
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # RORC/8278R

Concentration

0.2 mg/ml

View all ROR gamma/RORC/NR1F3 Antibodies »

Product Specifications

Immunogen

Recombinant full-length human ROR gamma protein

Localization

Nucleus

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Description

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.

Scientific Data Images for ROR gamma/RORC/NR1F3 Antibody (RORC/8278R)

ROR gamma/RORC/NR1F3 Antibody (RORC/8278R)

Immunohistochemistry-Paraffin: ROR gamma/RORC/NR1F3 Antibody (RORC/8278R) [NBP3-26721 ] -

Formalin-fixed, paraffin-embedded human pancreas stained with ROR gamma/RORC/NR1F3 Antibody (RORC/8278R). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Applications for ROR gamma/RORC/NR1F3 Antibody (RORC/8278R)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2ug/ml for 30 minutes at RT
Application Notes
Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT. Optimal dilution for a specific application should be determined.. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: ROR gamma/RORC/NR1F3

ROR gamma/RORC/NR1F3, aka RAR Orphan Receptor gamma, is a Nuclear Receptor 1 Thyroid Hormone-Like receptor containing a short A-T rich sequence follow by a single core motif half-site 5'-AGGTCA-3'. RORC is a key regulator of thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. NR1F3 regulates intrinsic transcriptional functions. Unlike other major nuclear receptors, RORC binds as a monomer to hormone response elements and is documented in mouse thymus, adipose, bone, skeletal muscle, liver, kidney, and human skeletal muscle. An N-terminal isoform of ROR gamma, ROR gamma T, inhibits Fas ligand expression and cytokine secretion in immature thymocytes.

Long Name

Retinoic Acid-Related Orphan Receptor gamma

Alternate Names

NR1F3, RORC, RZRG

Gene Symbol

RORC

Additional ROR gamma/RORC/NR1F3 Products

Product Documents for ROR gamma/RORC/NR1F3 Antibody (RORC/8278R)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ROR gamma/RORC/NR1F3 Antibody (RORC/8278R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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