ROR gamma/RORC/NR1F3 Antibody (RORC/8278R) [DyLight 650]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27002C

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Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-26721

Alexa Fluor 350

NBP3-27002AF350

Alexa Fluor 405

NBP3-27002AF405

Alexa Fluor 488

NBP3-27002AF488

Alexa Fluor 532

NBP3-27002AF532

Alexa Fluor 594

NBP3-27002AF594

Alexa Fluor 647

NBP3-27002AF647

Alexa Fluor 700

NBP3-27002AF700

Alexa Fluor 750

NBP3-27002AF750

Allophycocyanin

NBP3-27002APC

Biotin

NBP3-27002B

CoraFluor 1

NBP3-27002CL1

DyLight 350

NBP3-27002UV

DyLight 405

NBP3-27002V

DyLight 488

NBP3-27002G

DyLight 550

NBP3-27002R

DyLight 594

NBP3-27002DL594

DyLight 680

NBP3-27002FR

DyLight 755

NBP3-27002IR

FITC

NBP3-27002F

HRP

NBP3-27002H

Janelia Fluor 525

NBP3-27002JF525

Janelia Fluor 549

NBP3-27002JF549

Janelia Fluor 585

NBP3-27002JF585

Janelia Fluor 635

NBP3-27002JF635

Janelia Fluor 646

NBP3-27002JF646

Janelia Fluor 669

NBP3-27002JF669

mFluor Violet 450 SE

NBP3-27002MFV450

mFluor Violet 500 SE

NBP3-27002MFV500

mFluor Violet 610 SE

NBP3-27002MFV610

PE

NBP3-27002PE

PerCP

NBP3-27002PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-27002

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

DyLight 650 (Excitation = 652 nm, Emission = 672 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # RORC/8278R

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ROR gamma/RORC/NR1F3 Antibodies »

Product Summary for ROR gamma/RORC/NR1F3 Antibody (RORC/8278R) [DyLight 650]

Immunogen

Recombinant full-length human ROR gamma protein

Localization

Nucleus

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for ROR gamma/RORC/NR1F3 Antibody (RORC/8278R) [DyLight 650]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ROR gamma/RORC/NR1F3

ROR gamma/RORC/NR1F3, aka RAR Orphan Receptor gamma, is a Nuclear Receptor 1 Thyroid Hormone-Like receptor containing a short A-T rich sequence follow by a single core motif half-site 5'-AGGTCA-3'. RORC is a key regulator of thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. NR1F3 regulates intrinsic transcriptional functions. Unlike other major nuclear receptors, RORC binds as a monomer to hormone response elements and is documented in mouse thymus, adipose, bone, skeletal muscle, liver, kidney, and human skeletal muscle. An N-terminal isoform of ROR gamma, ROR gamma T, inhibits Fas ligand expression and cytokine secretion in immature thymocytes.

Long Name

Retinoic Acid-Related Orphan Receptor gamma

Alternate Names

NR1F3, RORC, RZRG

Gene Symbol

RORC

Additional ROR gamma/RORC/NR1F3 Products

Product Documents for ROR gamma/RORC/NR1F3 Antibody (RORC/8278R) [DyLight 650]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for ROR gamma/RORC/NR1F3 Antibody (RORC/8278R) [DyLight 650]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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