S-arrestin Antibody (PDS-1) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2385CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB100-2385AF350

Alexa Fluor 405

NB100-2385AF405

Alexa Fluor 488

NB100-2385AF488

Alexa Fluor 532

NB100-2385AF532

Alexa Fluor 594

NB100-2385AF594

Alexa Fluor 647

NB100-2385AF647

Alexa Fluor 700

NB100-2385AF700

Alexa Fluor 750

NB100-2385AF750

Biotin

NB100-2385B

DyLight 350

NB100-2385UV

DyLight 405

NB100-2385V

DyLight 488

NB100-2385G

DyLight 550

NB100-2385R

DyLight 594

NB100-2385DL594

DyLight 650

NB100-2385C

DyLight 680

NB100-2385FR

DyLight 755

NB100-2385IR

FITC

NB100-2385F

HRP

NB100-2385H

Janelia Fluor 525

NB100-2385JF525

Janelia Fluor 549

NB100-2385JF549

Janelia Fluor 585

NB100-2385JF585

Janelia Fluor 635

NB100-2385JF635

Janelia Fluor 646

NB100-2385JF646

Janelia Fluor 669

NB100-2385JF669

mFluor Violet 450 SE

NB100-2385MFV450

mFluor Violet 500 SE

NB100-2385MFV500

mFluor Violet 610 SE

NB100-2385MFV610

Forumulation

Catalog #

BSA Free

NB100-2385

Azide and BSA Free

NBP2-80937

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Porcine, Bovine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG₁ Clone # PDS-1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all S-arrestin Antibodies »

Product Summary for S-arrestin Antibody (PDS-1) [CoraFluor™ 1]

Immunogen

Porcine retinal S-arrestin [Swiss-Prot# P79260]

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for S-arrestin Antibody (PDS-1) [CoraFluor™ 1]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: S-arrestin

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. (provided by RefSeq)

Alternate Names

arrestin 1, RP47,48 kDa protein, S-antigen; retina and pineal gland (arrestin), S-arrestin, visual arrestin

Gene Symbol

SAG

Additional S-arrestin Products

Product Documents for S-arrestin Antibody (PDS-1) [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for S-arrestin Antibody (PDS-1) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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