SCAMP5 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB120-3432

Novus Biologicals, part of Bio-Techne
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NB120-3432
NB120-3432-0.025mg
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Key Product Details

Species Reactivity

Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all SCAMP5 Antibodies »

Product Specifications

Immunogen

Synthetic Peptide: C N(217) Q P Q T Q Y S A T P N Y T Y S N(233)

Reactivity Notes

Expected cross-reactivity with Mouse base on sequence identity.

Specificity

NB120-3432 immunizing peptide corresponds to amino acid residues 217-233 from rat SCAMP 5. This sequence is 94% conserved in mouse.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SCAMP5 Antibody - BSA Free

Western Blot: SCAMP5 AntibodyBSA Free [NB120-3432]

Western Blot: SCAMP5 AntibodyBSA Free [NB120-3432]

Western Blot: SCAMP5 Antibody [NB120-3432] - Analysis of rat brain extract.

Applications for SCAMP5 Antibody - BSA Free

Application
Recommended Usage

Western Blot

2 ug/ml
Application Notes
WB: Detects an approx. 25 kDa protein representing SCAMP 5 from rat brain extract.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SCAMP5

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

Alternate Names

DKFZp686L1799, hSCAMP5, MGC24969, Sc5, secretory carrier membrane protein 5, secretory carrier-associated membrane protein 5

Entrez Gene IDs

65171 (Rat)

Gene Symbol

SCAMP5

Additional SCAMP5 Products

Product Documents for SCAMP5 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SCAMP5 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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