SCAMP5 Antibody [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NB120-3432G

Novus Biologicals, part of Bio-Techne
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NB120-3432G
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NB120-3432
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Key Product Details

Species Reactivity

Rat

Applications

Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SCAMP5 Antibodies »

Product Specifications

Immunogen

Synthetic Peptide: C N(217) Q P Q T Q Y S A T P N Y T Y S N(233)

Reactivity Notes

Expected cross-reactivity with Mouse base on sequence identity.

Specificity

NB120-3432 immunizing peptide corresponds to amino acid residues 217-233 from rat SCAMP 5. This sequence is 94% conserved in mouse.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for SCAMP5 Antibody [DyLight 488]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: SCAMP5

Secretory Carrier Membrane Proteins (SCAMPs) are proteins that are components of post Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

Alternate Names

DKFZp686L1799, hSCAMP5, MGC24969, Sc5, secretory carrier membrane protein 5, secretory carrier-associated membrane protein 5

Gene Symbol

SCAMP5

Additional SCAMP5 Products

Product Documents for SCAMP5 Antibody [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SCAMP5 Antibody [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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