TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Long Name

Serine/threonine-protein kinase TAO1

Alternate Names

hKFC-B, hTAOK1, KIAA1361, MAP3K16, MARK Kinase, MARKK, PSK-2, PSK2, TAOK1

Gene Symbol

TAOK1

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Product Documents for TAO Kinase 1 Antibody (TAO1 1.2) [mFluor Violet 450 SE]

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Product Specific Notices for TAO Kinase 1 Antibody (TAO1 1.2) [mFluor Violet 450 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TAO Kinase 1 Antibody (TAO1 1.2) [mFluor Violet 450 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-50324MFV450

Key Product Details

Species Reactivity

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Product Specifications

Immunogen

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Isotype

Applications for TAO Kinase 1 Antibody (TAO1 1.2) [mFluor Violet 450 SE]

Immunocytochemistry/ Immunofluorescence

Knockdown Validated

Western Blot

Formulation, Preparation, and Storage

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Stability & Storage

Background: TAO Kinase 1