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TERT Antibody Pack

Novus Biologicals, part of Bio-Techne | Catalog # NB100-913

Novus Biologicals, part of Bio-Techne
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NB100-913-1Pack

Key Product Details

Species

Human, Mouse, Rat

Applications

Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Knockdown Validated, Western Blot

Product Summary for TERT Antibody Pack

This pack contains 1 vial each of: NB100-317 (0.1 mL) and NB100-297 (0.1 mL).

Product Specifications

Application Notes

See individual datasheets of components for their validated applications

Reactivity Notes

See individual datasheets of components for their validated species

Scientific Data Images for TERT Antibody Pack

Immunohistochemistry-Paraffin: TERT Antibody Pack [NB100-913]

Immunohistochemistry-Paraffin: TERT Antibody Pack [NB100-913]

Immunohistochemistry-Paraffin: TERT Antibody Pack [NB100-913] - TERT was detected in immersion fixed paraffin-embedded sections of human liver cancer using anti-human mouse monoclonal antibody (Catalog # NB100-297) at 1:600 dilution overnight at 4C. Tissue was stained using the VisuCyte anti-mouse HRP polymer detection reagent (Catalog # VC001) with DAB chromogen (brown) and counterstained with hematoxylin (blue). Images may not be copied, printed or otherwise disseminated without express written permission of Novus Biologicals a bio-techne brand.
Western Blot: TERT Antibody Pack [NB100-913]

Western Blot: TERT Antibody Pack [NB100-913]

Western Blot: TERT Antibody Pack [NB100-913] - Increased levels of IFI16 protein in WI-38 cells reduce hTERT levels and inhibit telomerase activity. Total protein extracts prepared from WI-38 cells, either transfected with control (pCMV) vector (lane 1) or pCMV-IFI16 plasmid (lane 2), were subjected to immunoblotting using antibodies specific to the indicated proteins. Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.pone.0008569), licensed under a CC-BY license. TERT Antibody (2C4) [NB100-317]
Immunohistochemistry-Paraffin: TERT Antibody Pack [NB100-913]

Immunohistochemistry-Paraffin: TERT Antibody Pack [NB100-913]

Immunohistochemistry-Paraffin: TERT Antibody Pack [NB100-913] - Normal human pancreas showing moderate TERT staining of exocrine cells and a subset of islets of Langerhans using TERT antibody (NB100-317).

Formulation, Preparation, and Storage

Concentration

Concentration of individual antibodies may be found on the vial label. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: TERT

Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase. Telomerase (TERT) is an enzyme uniquely associated with immortal cell lines and is useful for identifying undifferentiated PSCs.

Long Name

Telomerase Reverse Transcriptase

Alternate Names

EST2Telomerase-associated protein 2, hEST2, hTERT, TCS1EC 2.7.7.49, Telomerase catalytic subunit, telomerase reverse transcriptase, TP2HEST2, TRTEC 2.7.7

Gene Symbol

TERT

Additional TERT Products

Product Documents for TERT Antibody Pack

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TERT Antibody Pack

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Packs are guaranteed for 1 year from date of receipt.

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