Tie-2 Antibody (B-B48) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14575

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Alexa Fluor 350

NBP3-14575AF350

Alexa Fluor 405

NBP3-14575AF405

Alexa Fluor 488

NBP3-14575AF488

Alexa Fluor 532

NBP3-14575AF532

Alexa Fluor 594

NBP3-14575AF594

Alexa Fluor 647

NBP3-14575AF647

Alexa Fluor 700

NBP3-14575AF700

Alexa Fluor 750

NBP3-14575AF750

Allophycocyanin

NBP3-14575APC

Biotin

NBP3-14575B

CoraFluor 1

NBP3-14575CL1

DyLight 350

NBP3-14575UV

DyLight 405

NBP3-14575V

DyLight 488

NBP3-14575G

DyLight 550

NBP3-14575R

DyLight 594

NBP3-14575DL594

DyLight 650

NBP3-14575C

DyLight 680

NBP3-14575FR

DyLight 755

NBP3-14575IR

FITC

NBP3-14575F

HRP

NBP3-14575H

Janelia Fluor 525

NBP3-14575JF525

Janelia Fluor 549

NBP3-14575JF549

Janelia Fluor 646

NBP3-14575JF646

Janelia Fluor 669

NBP3-14575JF669

mFluor Violet 450 SE

NBP3-14575MFV450

mFluor Violet 500 SE

NBP3-14575MFV500

mFluor Violet 610 SE

NBP3-14575MFV610

PE

NBP3-14575PE

PerCP

NBP3-14575PCP

Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # B-B48

Format

Azide and BSA Free

Concentration

1 mg/ml

View all Tie-2 Antibodies »

Product Specifications

Immunogen

Eahy 926 cell line

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Description

Stable at 4C for 12 months.

Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells

Scientific Data Images for Tie-2 Antibody (B-B48) - Azide and BSA Free

Flow Cytometry: Tie-2 Antibody (B-B48) - Azide and BSA Free [NBP3-14575]

Flow Cytometry: Tie-2 Antibody (B-B48) [NBP3-14575] - A typical staining pattern with the B-B48 monoclonal antibody of Eahy 926 cell line.

Applications for Tie-2 Antibody (B-B48) - Azide and BSA Free

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Biological Activity: Inhibits Tek-L / Tek binding

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS. Sterile-filtered through 0.22 um.

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tie-2

TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.

Long Name

Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains 2

Alternate Names

CD202b, TEK, Tie2

Gene Symbol

TEK

Additional Tie-2 Products

Product Documents for Tie-2 Antibody (B-B48) - Azide and BSA Free

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Tie-2 Antibody (B-B48) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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