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Tollip Antibody (SB40a) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28621CL1

Novus Biologicals, part of Bio-Techne
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NBP1-28621CL1

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Western Blot

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # SB40a

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Tollip Antibody (SB40a) [CoraFluor™ 1]

Immunogen

Recombinant Tollip

Reactivity Notes

Human

Specificity

Human Tollip; Does not react to TLR2, TLR4, TLR6, TLR7, TLR8 and TLR10 recombinant proteins

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for Tollip Antibody (SB40a) [CoraFluor™ 1]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Tollip

TOLLIP is a ubiquitin-binding protein that interacts with several components of the Toll-like receptor (TLR; see MIM 603030) signaling cascade. It is an essential regulator of inflammatory signaling and is involved in trafficking of interleukin-1 receptor (IL1R; MIM 147810) and turnover of IL1R-associated kinase (IRAK, or IRAK1; MIM 300283) (summary by Lo et al., 2009 (PubMed 19444506)).(supplied by OMIM)

Long Name

Toll Interacting Protein

Alternate Names

IL-1RAcPIP

Gene Symbol

TOLLIP

Additional Tollip Products

Product Documents for Tollip Antibody (SB40a) [CoraFluor™ 1]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Tollip Antibody (SB40a) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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