ULBP-1 Antibody (MM0592-10K10) [mFluor Violet 610 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-11986MFV610

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Block/Neutralize, CyTOF-ready, Flow Cytometry

Label

mFluor Violet 610 SE (Excitation = 421 nm, Emission = 613 nm)

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0592-10K10

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ULBP-1 Antibodies »

Product Specifications

Immunogen

Human recombinant ULBP-1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Scientific Data Images for ULBP-1 Antibody (MM0592-10K10) [mFluor Violet 610 SE]

ULBP-1 Antibody (MM0592-10K10) [mFluor Violet 610 SE]

ULBP-1 Antibody (MM0592-10K10) [mFluor Violet 610 SE] [NBP2-11986MFV610] -

ULBP-1 Antibody (MM0592-10K10) [mFluor Violet 610 SE] [NBP2-11986MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.

Applications for ULBP-1 Antibody (MM0592-10K10) [mFluor Violet 610 SE]

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ULBP-1

Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked theinteraction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system.UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface

Long Name

UL16 Binding Protein-1

Alternate Names

ALCAN-beta, MULT-1, NKG2DL, NKG2DL1, RAET1I, ULBP1

Gene Symbol

ULBP1

Additional ULBP-1 Products

Product Documents for ULBP-1 Antibody (MM0592-10K10) [mFluor Violet 610 SE]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ULBP-1 Antibody (MM0592-10K10) [mFluor Violet 610 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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