Human Progranulin/PGRN ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80229

Novus Biologicals, part of Bio-Techne
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Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma and other biological fluids (100 ul)

Sensitivity

37.5 pg/mL

Assay Range

62.5-4000 pg/mL

View all Progranulin/PGRN ELISA Kits »

Product Specifications

Assay Type

Sandwich-ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Human

Specificity

This kit recognizes Human PGRN in samples. No significant cross-reactivity or interference between Human PGRN and analogues was observed.

Precision

Intra-Assay Precision (Precision within an assay) CV% < 5.01%

Inter-Assay Precision (Precision between assays) CV% < 4.96%

Recovery for Human Progranulin/PGRN ELISA Kit (Colorimetric)

Recovery

85-111%

Linearity

Human Progranulin/PGRN ELISA Kit (Colorimetric)

Scientific Data Images for Human Progranulin/PGRN ELISA Kit (Colorimetric)

Human Progranulin/PGRN ELISA Kit (Colorimetric)

ELISA: Human Progranulin/PGRN ELISA Kit (Colorimetric) [NBP2-80229] -

ELISA: Human Progranulin/PGRN ELISA Kit (Colorimetric) [NBP2-80229] - Standard Curve Reference

Kit Contents for Human Progranulin/PGRN ELISA Kit (Colorimetric)

  • Biotinylated Detection Ab Diluent
  • Concentrated Biotinylated Detection Ab (100X)
  • Concentrated HRP Conjugate (100X)
  • Concentrated Wash Buffer (25X)
  • HRP Conjugate Diluent
  • Micro ELISA Plate (Dismountable)
  • Plate Sealer
  • Product Manual
  • Reference Standard
  • Sample Diluent
  • Stop Solution
  • Substrate Reagent

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Progranulin/PGRN

Progranulin, also known as Acrogranin, PCDGF, and Epithelin/Granulin Precursor, is a widely expressed glycoprotein that can undergo proteolysis to generate numerous Granulin peptides. Progranulin plays a role in the regulation of mesothelial differentiation, macrophage development, sexual differentiation of the brain, cartilage proliferation, wound repair, and the development of rheumatoid arthritis and osteoarthritis. It is often upregulated in cancer and contributes to tumor progression. Progranulin upregulation or mutation is associated with several neurological disorders including frontotemporal dementia, Creutzfeldt-Jakob disease, Alzheimer’s disease, and motor neuron disease.

Alternate Names

Acrogranin, GEP, GP88, GRN, PCDGF, PEPI, PGRN, Proepithelin

Gene Symbol

GRN

Additional Progranulin/PGRN Products

Product Documents for Human Progranulin/PGRN ELISA Kit (Colorimetric)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Human Progranulin/PGRN ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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