SHP-1 Antibody Pair

Novus Biologicals, part of Bio-Techne | Catalog # H00005777-AP22

Novus Biologicals, part of Bio-Techne
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

1 ng/ml to 100 ng/ml

Reactivity

Human

View all SHP-1 ELISA Kits »

Product Specifications

Description

Quality control test: Standard curve using recombinant protein (H00005777-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human PTPN6.

Conjugate

Unconjugated

Application Notes

Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.

Scientific Data Images for SHP-1 Antibody Pair

Sandwich ELISA: PTPN6 Antibody Pair [H00005777-AP22] - Detection sensitivity ranging from 1 ng/ml to 100 ng/ml.

Kit Contents for SHP-1 Antibody Pair

  • Capture antibody: rabbit MaxPab affinity purified polyclonal anti-PTPN6 (100 ug)
  • Detection antibody: mouse purified polyclonal anti-PTPN6 (20 ug)

Preparation and Storage

Formulation

1x PBS, pH 7.4

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SHP-1

The SH2 domain-containing phosphatases, SHP-1 and SHP-2, are well-studied cytosolic tyrosine phosphatases that share many structural and regulatory features. They both have two tandem SH2 domains at the N-terminus, followed by a catalytic domain, and an inhibitory C-terminus. Despite their structural similarity, the enzymes appear to have different physiological roles and exhibit different expression patterns. SHP-1 is highly expressed in hematopoietic tissues, and in general has a negative impact on lymphocyte signaling. In contrast, SHP-2 is widely expressed, and in general promotes signaling pathways that lead to differentiation, cell growth, or migration.

Long Name

Src Homology Region 2 Domain Phosphatase 1

Alternate Names

HCPH, PTP1C, PTPN6, SHP1

Gene Symbol

PTPN6

Additional SHP-1 Products

Product Documents for SHP-1 Antibody Pair

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SHP-1 Antibody Pair

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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