Recombinant Human CCL26/Eotaxin-3 Protein

Name: Recombinant Human CCL26/Eotaxin-3 Protein
Brand: Novus Biologicals
SKU: NBP2-34982

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34982

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Product Datasheet / COA

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Accession #

Q9Y258

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

View all CCL26/Eotaxin-3 Proteins and Enzymes »

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 71 amino acid residues corresponding to CCL26/Eotaxin-3 Source: E. coli

Uniprot ID: Q9Y258

Amino Acid Sequence: TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L

Purity

> 97 % pure by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of CCL26/Eotaxin-3 as determined by LAL method.

Predicted Molecular Mass

8.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CCR3 transfected HEK293 cells is in a concentration range of 0.5-2.0 ug/ml.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CCL26/Eotaxin-3 Protein

SDS-PAGE: Recombinant Human CCL26/Eotaxin-3 Protein [NBP2-34982]

SDS-Page: Human CCL26/Eotaxin-3 Protein [NBP2-34982]

Formulation, Preparation and Storage

NBP2-34982

Formulation	Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.
Format	Carrier-Free
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: CCL26/Eotaxin-3

CCL26 is novel CC family chemokine, also known as TARC (thymus and activation regulated chemokine). It is encoded by CCL26 gene, which is located on Chr.7 in humans, and ubiquitously expressed at low levels in various tissues including heart and ovary. CCL26 elicits its effects activity by binding to the cell surface chemokine receptor CCR3, and chemotactic for eosinophils and basophils

Alternate Names

Eotaxin-3, Eotaxin3, SCYA26, CCL26, Eotaxin-3/CCL26

Gene Symbol

CCL26

UniProt