CCL26/Eotaxin-3 Products
CCL26, also known as Eotaxin-3 and SCYA26, is a small cytokine that is a member of the CC chemokine family. It is only 94 amino acids (aa) in length, with aa 1-23 serving as a putative signal peptide. Human CCL26/Eotaxin-3 has a predicted molecular weight of approximately 11 kDa, and the mature protein only shares 27% aa sequence identity with the mouse ortholog.
CCL26/Eotaxin-3 is constitutively expressed at low levels in various tissues including in the heart and ovary. Its expression is upregulated in vascular endothelial cells by IL-13 and IL-4. CCL26/Eotaxin-3 is a selective agonist for CCR3, as serves as a chemoattractant for cells that express CCR3, such as eosinophils, basophils, and Th2 cells. It has also been shown to act as an antagonist for the receptors CCR1 and CCR5. CCL26/Eotaxin-3 plays a role in allergic reactions.
Products:
19 results for "CCL26/Eotaxin-3" in Products
19 results for "CCL26/Eotaxin-3" in Products
CCL26/Eotaxin-3 Products
CCL26, also known as Eotaxin-3 and SCYA26, is a small cytokine that is a member of the CC chemokine family. It is only 94 amino acids (aa) in length, with aa 1-23 serving as a putative signal peptide. Human CCL26/Eotaxin-3 has a predicted molecular weight of approximately 11 kDa, and the mature protein only shares 27% aa sequence identity with the mouse ortholog.
CCL26/Eotaxin-3 is constitutively expressed at low levels in various tissues including in the heart and ovary. Its expression is upregulated in vascular endothelial cells by IL-13 and IL-4. CCL26/Eotaxin-3 is a selective agonist for CCR3, as serves as a chemoattractant for cells that express CCR3, such as eosinophils, basophils, and Th2 cells. It has also been shown to act as an antagonist for the receptors CCR1 and CCR5. CCL26/Eotaxin-3 plays a role in allergic reactions.
Products:
Sensitivity: | 0.215 pg/mL |
Applications: | ELISA |
Assay Range: | 3.13 - 200 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, Plasma) |
Simple Plex Human CCL26/Eotaxin-3 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD28, and wash buffer.
Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Assay Range: | 62.5 - 4,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #115002 |
Applications: | WB, Neut |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC, Neut |
Control for use with Human CCL26/Eotaxin-3 Simple Plex Cartridge Kit
Applications: | Ctrl, Simple Plex |
Source: | E. coli |
Accession #: | Q9Y258 |
Applications: | BA |
Source: | E. coli |
Accession #: | Q9Y258.1 |
Applications: | BA |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2152H |
Applications: | WB |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #115009 |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #115005 |
Applications: | ELISA |
Applications: | WB |
Applications: | ELISA, NULL |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Applications: | Simple Plex |
Contains 4 membranes - each spotted in duplicate with 31 different chemokine antibodies
For use with catalog number DCC260B
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Applications: | Bioactivity, PAGE |