Recombinant Human ICAT/CTNNBIP1 His Protein

Name: Recombinant Human ICAT/CTNNBIP1 His Protein
Brand: Novus Biologicals
SKU: NBP1-45266

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-45266

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Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all ICAT Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-81 of Human ICAT/CTNNBIP1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MNREGAPGKS PEEMYIQQKV RVLLMLRKMG SNLTASEEEF LRTYAGVVNS QLSQLPPHSI DQGAEDVVMA FSRSETEDRR Q

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

11.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human ICAT/CTNNBIP1 His Protein

SDS-PAGE: Recombinant Human ICAT/CTNNBIP1 His Protein [NBP1-45266]

SDS-Page: ICAT/CTNNBIP1 Protein [NBP1-45266] - 15% SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-45266

Formulation	20 mM Tris-HCl buffer (pH 8.0), 20% glycerol, 100 mM NaCl
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ICAT

CTNNBIP1 binds CTNNB1 and prevents interaction between CTNNB1 and TCF (T-cell transcription factor) family members. This protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. Recombinant human CTNNBIP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography

Long Name

Beta-Catenin-Interacting Protein

Alternate Names

CTNNBIP1

Gene Symbol