CoraFluor™ 1, Haloalkane
Tocris Bioscience, part of Bio-Techne | Catalog # 8817
Key Product Details
| Description: | Cell impermeable terbium cryptate FRET donor for TR-FRET assay development, with chloroalkane ligand |
| Molecular Weight: | 1524.93 |
Biological Activity for CoraFluor™ 1, Haloalkane
CoraFluor™ 1, Haloalkane is a cell impermeable terbium-based time-resolved Förster resonance energy transfer (TR-FRET) donor for TR-FRET assay development, such as target engagement and ternary complex assays. CoraFluor™ 1, Haloalkane is designed with chloroalkane ligand for reactivity with haloalkane dehalogenase labeled proteins. It is exceptionally bright, providing unmatched assay sensitivity and stability in biological media over other commercially available TR-FRET donors. CoraFluor™ 1, Haloalkane is compatible with common acceptor dyes such as FAM, TMR and Cyanine 5, SE (Cat. No. 5436), enabling seamless assay integration in high throughput screening applications.
CoraFluor™ 2, Haloalkane, CoraFluor™ 1, thiol reactive, CoraFluor™ 1, amine reactive and CoraFluor™ 2, amine reactive also available.
CoraFluor is a trademark of Bio-Techne Corp.
Licensing Information
Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254
Optical Data for CoraFluor™ 1, Haloalkane
| λabs | 340 nm |
|---|---|
| Extinction Coefficient (ε) | 21500 M-1cm-1 |
| Quantum Yield (φ) | 0.58 |
| Cell Permeable | No |
| Application | Time-resolved fluorescence energy transfer (TR-FRET) |