PI 828

Biological Activity for PI 828

Technical Data for PI 828

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for PI 828

References for PI 828

References are publications that support the biological activity of the product.

• Park, Meeyoung, Ohana, Ehud, Choi, Soo Youn, Lee, Myeong-S, Park, Jong Hoo, Muallem, Shmuel Multiple roles of the SO4(2-)/Cl-/OH- exchanger protein Slc26a2 in chondrocyte functions. J Biol Chem, 2014;289(4):1993-2001. 2014 PMID: 24302720
• Kulkarni A, Roy B, Rao P, Wyant G, Mahmoud A, Ramachandran M, Sengupta P, Goldman A, Kotamraju V, Basu S, Mashelkar R, Ruoslahti E, Dinulescu D, Sengupta S Supramolecular nanoparticles that target phosphoinositide-3-kinase overcome insulin resistance and exert pronounced antitumor efficacy. Cancer Res, 2013;73(23):6987-97. 2013 PMID: 24121488
• N Mahfouz, R Tahtouh, N Alaaeddine, J El Hajj, R Sarkis, R Hachem, I Raad, G Hilal Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1? and VEGF receptors PLoS ONE, 2017;12(6):e0179202. 2017 PMID: 28594907
• Gharbi et al. Exploring the specificity of the PI3K family inhibitor LY294002. Biochem.J., 2007;404:15 PMID: 17302559