17 results for "PI 3-Kinase Inhibitors" in Products
PI 3-Kinase Inhibitors Products
Inhibitor of PI 3-kinase, mTOR and DNA-PK
| Chemical Name: | 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride |
| Purity: | ≥98% (HPLC) |
PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130)
| Chemical Name: | 2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
| Chemical Name: | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride |
| Purity: | ≥99% (HPLC) |
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
| Chemical Name: | 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one |
| Purity: | ≥98% (HPLC) |
Non-selective PI 3-kinase inhibitor
| Chemical Name: | 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1
| Alternate Names: | SL-2052 |
| Chemical Name: | (1S,6bR,9aS,11R,11bR) 11-(Acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5,-h]-2-h]-2-benzopyran-3,6,9-trione |
| Purity: | ≥98% (HPLC) |
Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK
| Alternate Names: | GSK2126458 |
| Chemical Name: | 2,4-Difluoro-N-[2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective PI 3-kinase β inhibitor
| Chemical Name: | 7-Methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
Potent and selective PI 3-kinase p110α inhibitor
| Chemical Name: | (2S)-N1-[2-(1,1-Dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide |
| Purity: | ≥98% (HPLC) |
Potent PI3K inhibitor, also used in hPSCs mesendoderm differentiation
| Chemical Name: | N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
Dual DNA-PK and PI 3-K inhibitor
| Chemical Name: | 4-Ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piperazineacetamide |
| Purity: | ≥97% (HPLC) |
Class III PI 3-kinase inhibitor; also inhibits autophagy
| Alternate Names: | 3-MA |
| Chemical Name: | 3-Methyl-3H-purin-6-amine |
| Purity: | ≥99% (HPLC) |
Dual kinase inhibitor; inhibits PI 3-K family kinases
| Chemical Name: | 1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% (HPLC) |
Dual PI 3-kinase and PDPK1 (PDK1) inhibitor
| Chemical Name: | α,α,-Dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile |
| Purity: | ≥98% (HPLC) |
Potent and selective PI 3-Kβ inhibitor
| Chemical Name: | (-)-2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid |
| Purity: | ≥98% |
Potent PI 3-Kinase δ isoform inhibitor
| Chemical Name: | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone |
| Purity: | ≥98% (HPLC) |
Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines
| Chemical Name: | 1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one |
| Purity: | ≥98% (HPLC) |
