5-HT1D Products
5-HT1D is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of 5-HT1D is mediated by G proteins that inhibit adenylate cyclase activity. There is an association between polymorphisms within the genes encoding 5-HT1D and 5-HT1B with anorexia nervosa (AN). mRNA concentrations of the 5-HT1D receptor and the transcription factors, NUDR and REST, were significantly increased in dorsal raphe nucleus-captured neurons of female major depressive disorder subjects.
14 results for "5-HT1D" in Products
14 results for "5-HT1D" in Products
5-HT1D Products
5-HT1D is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of 5-HT1D is mediated by G proteins that inhibit adenylate cyclase activity. There is an association between polymorphisms within the genes encoding 5-HT1D and 5-HT1B with anorexia nervosa (AN). mRNA concentrations of the 5-HT1D receptor and the transcription factors, NUDR and REST, were significantly increased in dorsal raphe nucleus-captured neurons of female major depressive disorder subjects.
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
5-HT1A, 5-HT1B and 5-HT1D agonist
| Alternate Names: | GR 43175 |
| Chemical Name: | 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate |
| Purity: | ≥99% (HPLC) |
Potent and selective 5-HT1B and 5-HT1D antagonist
| Chemical Name: | N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
Selective 5-HT2A antagonist. Also antagonist at 5-HT1D
| Alternate Names: | R 41 468 |
| Chemical Name: | 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione tartrate |
| Purity: | ≥97% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1014728 |
| Applications: | IHC |
α partial agonist; also D2-like partial agonist and 5-HT antagonist
| Chemical Name: | 9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione mesylate |
| Purity: | ≥98% (HPLC) |
Potent 5-HT1B/1D/1F agonist
| Chemical Name: | (4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone |
| Purity: | ≥99% (HPLC) |
Highly selective 5-HT1D agonist
| Chemical Name: | (1S)-1-[2-[4-[4-(Aminocarbonyl)phenyl]-1-piperazinyl]ethyl]-3,4-dihydro-N-methyl-1H-2-benzopyran-6-carboxamide |
| Purity: | ≥98% (HPLC) |
Selective 5-HT1D antagonist
| Chemical Name: | 1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one hydrochloride |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Monkey |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: 5-HT1D Antibody - BSA Free [NLS590]](https://resources.bio-techne.com/images/products/5-HT1D-Antibody-Immunohistochemistry-Paraffin-NLS590-img0005.jpg "Immunohistochemistry-Paraffin: 5-HT1D Antibody - BSA Free [NLS590]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: 5-HT1D AntibodyAzide and BSA Free [NBP2-92762]](https://resources.bio-techne.com/images/products/5-HT1D-Antibody-Western-Blot-NBP2-92762-img0001.jpg "Western Blot: 5-HT1D AntibodyAzide and BSA Free [NBP2-92762]")
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human 5-HT1D GST (N-Term) Protein [H00003352-P01]](https://resources.bio-techne.com/images/products/qc_test-H00003352-P01-1.jpg "SDS-PAGE: Recombinant Human 5-HT1D GST (N-Term) Protein [H00003352-P01]")