Adenosine A2a Receptor Agonists: Small Molecules and Peptides
Adenosine A2A Receptor (ADORA2A) is one of several receptor subtypes for adenosine. The activity of ADORA2A, a G protein-coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. ADORA2A is abundant in basal ganglia, vasculature and platelets and is a major target of caffeine. Variability in the acute blood pressure response to coffee may be partly explained by genetic polymorphisms of the adenosine A2A receptors, including ADORA2A, and alpha(2)-adrenergic receptors.
3 results for "Adenosine A2a Receptor Agonists Small Molecules and Peptides" in Products
3 results for "Adenosine A2a Receptor Agonists Small Molecules and Peptides" in Products
Adenosine A2a Receptor Agonists: Small Molecules and Peptides
Adenosine A2A Receptor (ADORA2A) is one of several receptor subtypes for adenosine. The activity of ADORA2A, a G protein-coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. ADORA2A is abundant in basal ganglia, vasculature and platelets and is a major target of caffeine. Variability in the acute blood pressure response to coffee may be partly explained by genetic polymorphisms of the adenosine A2A receptors, including ADORA2A, and alpha(2)-adrenergic receptors.
A2A agonist
| Chemical Name: | 4-[2-[[6-Amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent adenosine A2A and A2B receptor partial agonist
| Chemical Name: | 2-Amino-4-(4-hydroxyphenyl)-6-[(1H-imidazol-2-ylmethyl)thio]-3,5-pyridinecarbonitrile |
| Purity: | ≥98% (HPLC) |
Potent adenosine A2A agonist
| Chemical Name: | 4-[2-[(6-Amino-9-b-D-ribofuranosyl-9H-purin-2-yl)thio]ethyl]benzenesulfonic acid ammonium salt |
| Purity: | ≥97% (HPLC) |
