Angiopoietin-2 Products
Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that regulates vascular remodeling by promoting endothelial cell survival, proliferation, and migration and destabilizing the interaction between EC and perivascular cells. Ang-2 is required for postnatal vascular remodeling, and it cooperates with Ang-1 during lymphatic vessel development. It mediates the upregulation of ICAM-1 and VCAM-1 on EC, which facilitates the adhesion of leukocytes during inflammation. Its direct interaction with Integrins promotes tumor cell invasion. Ang-2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It associates into dimers, trimers, and larger multimers and binds the receptor Tie-2, with its function as an agonist or antagonist depending on its state of multimerization.
242 results for "Angiopoietin-2" in Products
242 results for "Angiopoietin-2" in Products
Angiopoietin-2 Products
Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that regulates vascular remodeling by promoting endothelial cell survival, proliferation, and migration and destabilizing the interaction between EC and perivascular cells. Ang-2 is required for postnatal vascular remodeling, and it cooperates with Ang-1 during lymphatic vessel development. It mediates the upregulation of ICAM-1 and VCAM-1 on EC, which facilitates the adhesion of leukocytes during inflammation. Its direct interaction with Integrins promotes tumor cell invasion. Ang-2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It associates into dimers, trimers, and larger multimers and binds the receptor Tie-2, with its function as an agonist or antagonist depending on its state of multimerization.
| Sensitivity: | 21.3 pg/mL |
| Applications: | ELISA |
| Assay Range: | 46.9 - 3,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva) |
| Source: | NS0 |
| Accession #: | O15123 |
| Applications: | BA, BA |
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Simple Plex Human Angiopoietin-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Applications: | Simple Plex |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Assay Range: | 93.8 - 6,000 pg/mL |
| Applications: | ELISA |
| Sensitivity: | 4.98 pg/mL |
| Applications: | ELISA |
| Assay Range: | 39.1 - 2,500 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma) |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #85816 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #180102 |
| Applications: | WB |
| Source: | CHO |
| Accession #: | NP_031452 |
| Applications: | BA |
Control for use with Human Angiopoietin-2 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
Simple Plex Mouse/Rat Angiopoietin-2/ANG-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG2 Monoclonal Clone #MEDI3617 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #85834 |
For use with catalog numbers DANG20, SANG20, PDANG20
| Applications: | Ctrl |
Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #748246 |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #85834R |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Chicken, Avian - Chicken |
| Details: | Mouse IgG2 Monoclonal Clone #MM0020-1F29 |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Angiopoietin-2 Antibody (MM0020-1F29) - Azide and BSA Free [NB110-85467]](https://resources.bio-techne.com/images/products/Angiopoietin-2-Antibody-MM0020-1F29-Immunocytochemistry-Immunofluorescence-NB110-85467-img0004.jpg "Immunocytochemistry/ Immunofluorescence: Angiopoietin-2 Antibody (MM0020-1F29) - Azide and BSA Free [NB110-85467]")