CCL3/MIP-1 alpha Products
CCL3/MIP-1 alpha, is a beta chemokine that can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. It forms complexes with sulfated proteoglycans and also associates into noncovalently-linked dimers and high molecular weight polymers. These complexes of CCL3 are protected from proteolytic digestion by insulin degrading enzyme (IDE) which can cleave the monomeric chemokine. CCL3 signals through CCR1, CCR3, and CCR5, and it is internalized by the decoy chemokine receptor D6. CCL3 promotes the chemoattraction, adhesion to activated vascular endothelium, and cellular activation of many hematopoietic cell types. It can promote tumor metastasis, hyperalgesia, and inflammation and suppress HIV replication and hematopoietic stem cell proliferation.
115 results for "CCL3/MIP-1 alpha" in Products
115 results for "CCL3/MIP-1 alpha" in Products
CCL3/MIP-1 alpha Products
CCL3/MIP-1 alpha, is a beta chemokine that can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. It forms complexes with sulfated proteoglycans and also associates into noncovalently-linked dimers and high molecular weight polymers. These complexes of CCL3 are protected from proteolytic digestion by insulin degrading enzyme (IDE) which can cleave the monomeric chemokine. CCL3 signals through CCR1, CCR3, and CCR5, and it is internalized by the decoy chemokine receptor D6. CCL3 promotes the chemoattraction, adhesion to activated vascular endothelium, and cellular activation of many hematopoietic cell types. It can promote tumor metastasis, hyperalgesia, and inflammation and suppress HIV replication and hematopoietic stem cell proliferation.
| Sensitivity: | 10 pg/mL |
| Applications: | ELISA |
| Assay Range: |
31.2 - 1,000 pg/mL (Cell Culture Supernates) 46.9 - 1,500 pg/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Sensitivity: | 1.5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 4.7 - 300 pg/mL (Cell Culture Supernates, Serum) |
Simple Plex Human CCL3/MIP-1 alpha assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Simple Plex Mouse CCL3/MIP-1 alpha assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Source: | E. coli |
| Accession #: | P10147 |
| Applications: | BA |
| Assay Range: | 7.81 - 500 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.81 - 500 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Source: | E. coli |
| Accession #: | Q5QNW0 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #39624 |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #769324 |
| Applications: | WB, Neut |
Control for use with Human and Non-Human Primate CCL3/MIP-1 alpha Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #14215 |
| Applications: | ELISA, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #756605 |
| Applications: | Neut |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #39624 |
| Applications: | ICFlow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #39624 |
| Applications: | ICFlow |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #755012 |
| Applications: | WB |
| Reactivity: | Canine |
| Details: | Mouse IgG2a Monoclonal Clone #750521 |
| Applications: | WB |
| Reactivity: | Cotton Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #756613 |
| Applications: | WB, ICC |
