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Common beta Chain Products

The high-affinity receptors for Interleukin-3 (IL-3), IL-5, and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) consist of a cytokine-specific a chain, and a shared common beta chain subunit (CD131) that is essential for receptor signaling. CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective heteroreceptor complex. Phosphorylation of CD131 following receptor activation imparts growth and survival signals to the responding hematopoietic cells.

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93 results for "Common beta Chain" in Products

93 results for "Common beta Chain" in Products

Common beta Chain Products

The high-affinity receptors for Interleukin-3 (IL-3), IL-5, and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) consist of a cytokine-specific a chain, and a shared common beta chain subunit (CD131) that is essential for receptor signaling. CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective heteroreceptor complex. Phosphorylation of CD131 following receptor activation imparts growth and survival signals to the responding hematopoietic cells.

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Applications: BA
Applications: IHC, WB
Reactivity: Human
Applications: IHC, WB
Reactivity: Human
Applications: ELISA
Reactivity: Human

Recombinant monoclonal antibody expressed in HEK293F cells

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: WB, Flow
Reactivity: Human
Applications: ELISA
Applications: ELISA
Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, WB
Reactivity: Human
Applications: IHC, WB
Reactivity: Human
Applications: IHC, WB
Reactivity: Human
Applications: IHC, WB
Reactivity: Human
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, WB
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

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