COX-1 Products
Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.
56 results for "COX-1" in Products
56 results for "COX-1" in Products
COX-1 Products
Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.
Cyclooxygenase-1 (COX-1) inhibitor
| Chemical Name: | 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole |
| Purity: | ≥98% (HPLC) |
Cyclooxygenase inhibitor; NSAID
| Chemical Name: | 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt |
| Purity: | ≥99% |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Simple Western |
![Immunohistochemistry-Paraffin: COX-1 Antibody [NBP1-85500]](https://resources.bio-techne.com/images/products/COX-1-Antibody-Immunohistochemistry-Paraffin-NBP1-85500-img0012.jpg "Immunohistochemistry-Paraffin: COX-1 Antibody [NBP1-85500]")
Cyclooxygenase inhibitor (COX-1 > COX-2)
| Chemical Name: | 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #596002 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: COX-1 Antibody [NB100-867]](https://resources.bio-techne.com/images/products/COX-1-Antibody-Western-Blot-NB100-867-img0010.jpg "Western Blot: COX-1 Antibody [NB100-867]")
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SC68-05 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Western Blot: COX-1 Antibody (SC68-05) [NBP2-67643]](https://resources.bio-techne.com/images/products/COX-1-Antibody-SC68-05-Western-Blot-NBP2-67643-img0011.jpg "Western Blot: COX-1 Antibody (SC68-05) [NBP2-67643]")
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #345305 |
| Applications: | WB, Flow, CyTOF-ready |
Cyclooxygenase inhibitor; may be selective for COX-3
| Chemical Name: | N-(4-Hydroxyphenyl)acetamide |
| Purity: | ≥99% |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S02-6G4 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: COX-1 Antibody (S02-6G4) [NBP3-19609]](https://resources.bio-techne.com/images/products/COX-1-Antibody-S02-6G4-Western-Blot-NBP3-19609-img0003.jpg "Western Blot: COX-1 Antibody (S02-6G4) [NBP3-19609]")
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #345305 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #345305 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #345305 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #345305 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #345305 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #345305 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rat IgG2a Monoclonal Clone #345305 |
| Applications: | Flow |
NSAID, cyclooxygenase (COX-1) inhibitor. Also opener of KIR2.3
| Chemical Name: | (Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide |
| Purity: | ≥99% |
Cyclooxygenase inhibitor
| Chemical Name: | 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol |
| Purity: | ≥98% (HPLC) |
Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6
| Chemical Name: | 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid |
| Purity: | ≥99% (HPLC) |
| Applications: | ELISA |
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human COX-1 GST (N-Term) Protein [H00005742-P01]](https://resources.bio-techne.com/images/products/qc_test-H00005742-P01-1.jpg "SDS-PAGE: Recombinant Human COX-1 GST (N-Term) Protein [H00005742-P01]")
Cyclooxygenase (COX-1) inhibitor
| Chemical Name: | 1-[[4,5-bis(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride |
| Purity: | ≥98% (HPLC) |
