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DEK Products

The DEK oncogene is an approximately 45 kDa phosphoprotein with pleiotropic activities. It is a chromatin remodeling factor, a transcriptional coactivator and corepressor, a component of RNA spliceosomes, and a promoter of DNA repair during apoptosis. DEK is upregulated in many cancers and promotes epithelial cell transformation. It functions as a proinflammatory factor when secreted by activated macrophages. It is an autoantigen in juvenile arthritis and lupus and a target of chromosomal translocation with the CAN gene in acute myelogenous leukemia. DEK contains one SAP domain (aa 149-183), one nuclear localization sequence (aa 205-221), and a DNA-binding C-terminal domain (aa 321-375).

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103 results for "DEK" in Products

103 results for "DEK" in Products

DEK Products

The DEK oncogene is an approximately 45 kDa phosphoprotein with pleiotropic activities. It is a chromatin remodeling factor, a transcriptional coactivator and corepressor, a component of RNA spliceosomes, and a promoter of DNA repair during apoptosis. DEK is upregulated in many cancers and promotes epithelial cell transformation. It functions as a proinflammatory factor when secreted by activated macrophages. It is an autoantigen in juvenile arthritis and lupus and a target of chromosomal translocation with the CAN gene in acute myelogenous leukemia. DEK contains one SAP domain (aa 149-183), one nuclear localization sequence (aa 205-221), and a DNA-binding C-terminal domain (aa 321-375).

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Applications: IHC, ICC
Reactivity: Human
Applications: WB, IHC
Reactivity: Human
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse
Applications: IHC, WB, ICC/IF
Reactivity: Human, Rat

Recombinant Monoclonal Antibody

Applications: IHC, ELISA, ICC/IF, Flow
Reactivity: Human

Recombinant monoclonal antibody expressed in HEK293F cells

Applications: IHC, WB, IP
Reactivity: Human
Applications: WB, ICC/IF, IP
Reactivity: Human
Applications: IHC
Reactivity: Human
Applications: IHC, IP, WB (-)
Reactivity: Human
Applications: ICC/IF
Reactivity: Human
Applications: WB
Applications: AC
Applications: AC
Applications: IHC, IP, WB (-)
Reactivity: Human
Applications: ICC/IF
Reactivity: Human
Applications: WB, ICC/IF, IP
Reactivity: Human
Applications: IHC, IP, WB (-)
Reactivity: Human
Applications: IHC, IP, WB (-)
Reactivity: Human
Applications: IHC, IP, WB (-)
Reactivity: Human
Applications: IHC, IP, WB (-)
Reactivity: Human
Applications: ICC/IF
Reactivity: Human
Applications: WB, ICC/IF, IP
Reactivity: Human
Applications: ICC/IF
Reactivity: Human
Applications: ICC/IF
Reactivity: Human
Applications: WB, ICC/IF, IP
Reactivity: Human
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