Histamine H3 Receptor Antagonists: Small Molecules and Peptides
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors Histamine H1 R, Histamine H2 R, Histamine H3 R and Histamine H4 R. HRH3 encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. Histamine H3 R is an integral membrane protein and can regulate neurotransmitter release. It can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
4 results for "Histamine H3 Receptor Antagonists Small Molecules and Peptides" in Products
4 results for "Histamine H3 Receptor Antagonists Small Molecules and Peptides" in Products
Histamine H3 Receptor Antagonists: Small Molecules and Peptides
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors Histamine H1 R, Histamine H2 R, Histamine H3 R and Histamine H4 R. HRH3 encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. Histamine H3 R is an integral membrane protein and can regulate neurotransmitter release. It can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
High affinity H3 antagonist
| Chemical Name: | 1-[3-[4-(1-Piperidinylmethyl)phenoxy]propyl]piperidine hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent, selective H3 antagonist
| Chemical Name: | N-[2-(4-Iodophenyl)ethyl]-S-[3-(4(5)-imidazolyl)propyl]isothiourea dihydrobromide |
| Purity: | ≥98% (HPLC) |
H3 antagonist; also H4 inverse agonist
| Chemical Name: | N-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide |
| Purity: | ≥99% (HPLC) |
Highly potent H3 antagonist and H4 partial agonist
| Alternate Names: | VUF 9153 |
| Chemical Name: | N-(4-Chlorobenzyl)-S-[3-(4(5)-imidazolyl)propyl]isothiourea dihydrobromide |
| Purity: | ≥99% (HPLC) |
