IL-13 Products
IL-13 (Interleukin-13) plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. It promotes B cell activation, immunoglobulin class switching to IgE, and the upregulation of CD23/Fc epsilon RII. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 R alpha 2 binds IL-13 and prevents IL-13 from signaling through the IL-13 R alpha 1/IL-4 R alpha complex. IL-13-bound IL-13 R alpha 2 can directly promote tumor cell invasiveness and the development of tissue fibrosis.
556 results for "IL-13" in Products
556 results for "IL-13" in Products
IL-13 Products
IL-13 (Interleukin-13) plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. It promotes B cell activation, immunoglobulin class switching to IgE, and the upregulation of CD23/Fc epsilon RII. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 R alpha 2 binds IL-13 and prevents IL-13 from signaling through the IL-13 R alpha 1/IL-4 R alpha complex. IL-13-bound IL-13 R alpha 2 can directly promote tumor cell invasiveness and the development of tissue fibrosis.
Analyzed by SEC-MALS
| Source: | E. coli |
| Accession #: | AAK53823 |
| Applications: | BA |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Sensitivity: | 1.5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.8 - 500 pg/mL (Cell Culture Supernates) |
| Reactivity: | Non-human Primate |
| Details: | Mouse IgG1 Monoclonal Clone #IL13-I |
| Applications: | ELISA |
Analyzed by SEC-MALS
| Source: | E. coli |
| Accession #: | P20109 |
| Applications: | BA |
| Sensitivity: | 57.4 pg/mL |
| Applications: | ELISA |
| Assay Range: | 125 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Assay Range: | 93.8 - 6,000 pg/mL |
| Applications: | ELISA |
Simple Plex Human IL-13 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #38213 |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #32116 |
| Applications: | Flow, CyTOF-ready, Neut |
| Source: | E. coli |
| Accession #: | P42203 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, CyTOF-ready, ICFlow, Neut |
| Source: | E. coli |
| Accession #: | Q9N0W9 |
| Applications: | BA |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #31606 |
| Applications: | WB, CyTOF-ready, ICFlow, Neut |
Control for use with Human and Non-Humna Primate IL-13 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #296202 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #32116 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #32007 |
| Applications: | ICFlow |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
