IL-4 Products
IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R alpha and the common gamma chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R alpha and IL-13 R alpha 1. The type II receptor also transduces IL-13 mediated signals.
209 results for "IL-4" in Products
209 results for "IL-4" in Products
IL-4 Products
IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R alpha and the common gamma chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R alpha and IL-13 R alpha 1. The type II receptor also transduces IL-13 mediated signals.
Reactivity: | Feline |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #286120 |
Applications: | Neut |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | ICFlow |
Reactivity: | Cotton Rat |
Details: | Goat IgG Polyclonal |
Applications: | WB, Neut |
Reactivity: | Cotton Rat |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Rabbit |
Details: | Mouse IgG2b Monoclonal Clone #855824 |
Applications: | Neut |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | ICFlow |
Source: | E. coli |
Accession #: | P30367.2 |
Applications: | BA |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | ICFlow |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | ICFlow |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | ICFlow |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | ICFlow |
Source: | E. coli |
Accession #: | NP_001156649 |
Applications: | BA |
Reactivity: | Fish |
Details: | Mouse IgG Monoclonal Clone #V17P1B4*B12 |
Applications: | WB, ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #101 |
Applications: | ELISA |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rabbit IgG Kappa Monoclonal Clone #11B11 |
Applications: | IHC, ELISA, Flow, CyTOF-ready, Func |
Applications: | WB |
Applications: | ELISA |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal |
Applications: | ELISA, Flow, Func |
Reactivity: | Mouse |
Details: | Rat IgG1 Monoclonal Clone #11B11 |
Applications: | B/N |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal |
Applications: | ELISA, Flow, Func |
Applications: | Bioactivity, PAGE |
Applications: | Bioactivity, PAGE |
Applications: | Bioactivity, PAGE |
Applications: | Bioactivity, PAGE |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rabbit IgG Kappa Monoclonal Clone #11B11 |
Applications: | IHC, ELISA, Flow, CyTOF-ready, Func |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal |
Applications: | ELISA, Flow, Func |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rabbit IgG Kappa Monoclonal Clone #11B11 |
Applications: | IHC, ELISA, Flow, CyTOF-ready, Func |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |
Reactivity: | Porcine |
Details: | Mouse IgG1 Monoclonal Clone #99605 |
Applications: | WB, Flow, CyTOF-ready |