19 results for "iPSC Generation" in Products
iPSC Generation Products
Highly selective GSK-3 inhibitor; acts as Wnt activator
| Alternate Names: | CHIR99021,CT99021 |
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥98% (HPLC) |
EZH2 histone methyltransferase inhibitor
| Alternate Names: | DZNep,NSC 617989 |
| Chemical Name: | (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective inhibitor of TGF-βRI
| Alternate Names: | E-616452,SJN 2511,ALK5 Inhibitor II |
| Chemical Name: | 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine |
| Purity: | ≥99% (HPLC) |
Potent inhibitor of MEK1/2
| Alternate Names: | PD325901 |
| Chemical Name: | N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide |
| Purity: | ≥99% (HPLC) |
Enhances the generation of iPSCs; increases reprogramming efficiency
| Alternate Names: | L-Ascorbate,Vitamin C |
| Chemical Name: | 3-Oxo-L-gulofuranolactone |
| Purity: | ≥99% (HPLC) |
Histone deacetylase inhibitor
| Alternate Names: | VPA,Sodium Valproate |
| Chemical Name: | Sodium 2-propylpentanoate |
ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs
| Chemical Name: | N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide |
| Purity: | ≥98% (HPLC) |
Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥97% (HPLC) |
L-Ascorbic acid synthesized to Ancillary Material Grade
| Chemical Name: | 3-Oxo-L-gulofuranolactone |
| Purity: | ≥99% |
GSK-3β inhibitor; also inhibits cdks
| Chemical Name: | 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one |
| Purity: | ≥98% (HPLC) |
Retinoic acid analog; RAR agonist
| Alternate Names: | Ro 13-7410 |
| Chemical Name: | 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
DNA methyltransferase inhibitor
| Chemical Name: | 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one |
| Purity: | ≥98% (HPLC) |
RepSox synthesized to Ancillary Material Grade
| Alternate Names: | ALK5 Inhibitor II,SJN 2511,E-616452 |
| Chemical Name: | 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine |
| Purity: | ≥99% |
CaV1.x activator
| Chemical Name: | 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester |
| Purity: | ≥98% (HPLC) |
Irreversible inhibitor of LSD1; also inhibits MAO
| Alternate Names: | 2-PCPA |
| Chemical Name: | (±)-trans-2-Phenylcyclopropylamine hydrochloride |
| Purity: | ≥98% (HPLC) |
3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade
| Chemical Name: | (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride |
| Purity: | ≥98% |
Inhibitor of p53-mitochondrial binding
| Alternate Names: | NSC 303580 |
| Chemical Name: | 2-Phenylethynesulfonamide |
| Purity: | ≥99% (HPLC) |
GLP and G9a inhibitor
| Chemical Name: | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride |
| Purity: | ≥98% (HPLC) |
Non-nucleoside DNA methyltransferase inhibitor
| Chemical Name: | N-Phthalyl-L-tryptophan |
| Purity: | ≥99% (HPLC) |
