Isocitrate Dehydrogenase 1/IDH1: Small Molecules and Peptides
Isocitrate dehydrogenase 1 (IDH1) EC:1.1.1.42 is one of three isocitrate dehydrogenase isoforms found in humans. If mutated, IDH1 catalyzes α-KG to D-2-hydroxyglutarate (D2HG). It has als been linked to tumorigenesis in certain types of cancers.
Products:
2 results for "Isocitrate Dehydrogenase 1/IDH1 Small Molecules and Peptides" in Products
2 results for "Isocitrate Dehydrogenase 1/IDH1 Small Molecules and Peptides" in Products
Isocitrate Dehydrogenase 1/IDH1: Small Molecules and Peptides
Isocitrate dehydrogenase 1 (IDH1) EC:1.1.1.42 is one of three isocitrate dehydrogenase isoforms found in humans. If mutated, IDH1 catalyzes α-KG to D-2-hydroxyglutarate (D2HG). It has als been linked to tumorigenesis in certain types of cancers.
Products:
Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1)
| Chemical Name: | N-[2-(Cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-2-methyl-1H-Imidazole-1-acetamide |
| Purity: | ≥98% |
Potent inhibitor of mutant isocitrate dehydrogenase (mIDH1)
| Chemical Name: | (2S)-N-{(1S)-1-(2-Chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide |
| Purity: | ≥98% |
