LILRB4/CD85k/ILT3: Proteins and Enzymes
LILRB4, also known as ILT3, CD85k, and LIR-5, is a transmembrane glycoprotein that is expressed on dendritic cells (DC), monocytes, macrophages, and vascular endothelial cells (EC). Ligation of LILRB4 triggers ITIM-mediated inhibition of cell-activating signaling, leading to enhanced immune tolerance and reduced allogeneic graft rejection.
Soluble LILRB4 induces the differentiation of CD8+ T suppressor cells (Ts) that can inhibit the effector functions of CD4+ Th cells and CD8+ CTL. In turn, CD8+ Ts cells induce LILRB4 upregulation and a tolerogenic phenotype in monocytes, DC, and EC.
Products:
4 results for "LILRB4/CD85k/ILT3 Proteins and Enzymes" in Products
4 results for "LILRB4/CD85k/ILT3 Proteins and Enzymes" in Products
LILRB4/CD85k/ILT3: Proteins and Enzymes
LILRB4, also known as ILT3, CD85k, and LIR-5, is a transmembrane glycoprotein that is expressed on dendritic cells (DC), monocytes, macrophages, and vascular endothelial cells (EC). Ligation of LILRB4 triggers ITIM-mediated inhibition of cell-activating signaling, leading to enhanced immune tolerance and reduced allogeneic graft rejection.
Soluble LILRB4 induces the differentiation of CD8+ T suppressor cells (Ts) that can inhibit the effector functions of CD4+ Th cells and CD8+ CTL. In turn, CD8+ Ts cells induce LILRB4 upregulation and a tolerogenic phenotype in monocytes, DC, and EC.
Products:
| Source: | NS0 |
| Accession #: | AAH26309 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | NP_001265355.2 |
| Applications: | BA |
Fc Chimera
| Source: | CHO |
| Accession #: | XP_015297198.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q64281 |
| Applications: | BA |
