Mcl-1 Products
Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.
70 results for "Mcl-1" in Products
70 results for "Mcl-1" in Products
Mcl-1 Products
Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Western Blot: Mcl-1 Antibody (OTI10F6) [NBP2-45773]](https://resources.bio-techne.com/images/products/Mcl-1-Antibody-OTI10F6-Western-Blot-NBP2-45773-img0009.jpg "Western Blot: Mcl-1 Antibody (OTI10F6) [NBP2-45773]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat, Canine, Feline |
| Details: | Rabbit IgG Monoclonal Clone #HL1544 |
| Applications: | IHC, WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SI16-04 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Western Blot: Mcl-1 Antibody (SI16-04) [NBP2-67400]](https://resources.bio-techne.com/images/products/Mcl-1-Antibody-SI16-04-Western-Blot-NBP2-67400-img0010.jpg "Western Blot: Mcl-1 Antibody (SI16-04) [NBP2-67400]")
| Source: | E. coli |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S04-3A4 |
| Applications: | WB, ICC/IF |
![Western Blot: Mcl-1 Antibody (S04-3A4) [NBP3-19546]](https://resources.bio-techne.com/images/products/Mcl-1-Antibody-S04-3A4-Western-Blot-NBP3-19546-img0002.jpg "Western Blot: Mcl-1 Antibody (S04-3A4) [NBP3-19546]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
![Mcl-1 Antibody (OTI10F6) [mFluor Violet 500 SE]](https://resources.bio-techne.com/images/products/nbp2-72598mfv500_mouse-mcl-1-mab-oti10f6-mfluor-violet-500-se-57202313225682.png "Mcl-1 Antibody (OTI10F6) [mFluor Violet 500 SE] -")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
![Mcl-1 Antibody (OTI10F6) [mFluor Violet 610 SE]](https://resources.bio-techne.com/images/products/nbp2-72598mfv610_mouse-mcl-1-mab-oti10f6-mfluor-violet-610-se-67202399432.png "Mcl-1 Antibody (OTI10F6) [mFluor Violet 610 SE] [NBP2-72598MFV610] -")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI10F6 |
| Applications: | IHC, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL1128 |
| Applications: | IHC, WB, ICC/IF |