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NFX1 Products

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
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68 results for "NFX1" in Products

68 results for "NFX1" in Products

NFX1 Products

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
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Applications: WB, ELISA, ICC/IF
Reactivity: Human
Catalog #: H00004799-Q01
Applications: WB, ELISA, MA, AP, PAGE
Applications: WB, IP
Reactivity: Human, Mouse
Applications: IHC
Reactivity: Human
Applications: ICC/IF
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB
Applications: IP, WB (-)
Reactivity: Human
Applications: AC
Applications: AC
Applications: IP, WB (-)
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
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