NPY Receptor Antagonists: Small Molecules and Peptides
From the family of Gi/o-protein-coupled receptors, Neuropeptide Y (NPY) are divided into four subtypes: Y1, Y2, Y4 and Y5. NPY receptors mediate a diverse range of biological actions. These include stimulation of food intake and modulation of circadian rhythm.
9 results for "NPY Receptor Antagonists Small Molecules and Peptides" in Products
9 results for "NPY Receptor Antagonists Small Molecules and Peptides" in Products
NPY Receptor Antagonists: Small Molecules and Peptides
NPY Y2 receptor antagonist
| Chemical Name: | N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide |
| Purity: | ≥99% (HPLC) |
Highly selective NPY Y1 receptor antagonist
| Chemical Name: | N-[(1R)-1-[[[[4-[[(Aminocarbonyl)amino]methyl]phenyl]methyl]amino]carbonyl]-4-[(aminoiminomethyl)amino]butyl]-α-phenyl-benzeneacetamide ditrifluoroacetate |
| Purity: | ≥98% (HPLC) |
Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo
| Alternate Names: | BIIE 0246 2HCl,BIIE0246 2HCl |
| Chemical Name: | N-[(1S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent, competitive NPY Y1 receptor antagonist
| Chemical Name: | 1,4-Dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-dimethyl ester L-Lactate |
| Purity: | ≥99% (HPLC) |
Mixed NPY Y1 and NPFF receptor antagonist
| Chemical Name: | N-[(1R)]-4-[(Aminoiminomethyl)amino-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl-α-phenylbenzeneacetamide trifluoroacetate |
| Purity: | ≥98% (HPLC) |
Potent, selective non-peptide NPY Y5 receptor antagonist
| Chemical Name: | 5,5-Dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1oxo-1H-xanthen-9-yl)-1,3-cyclohexanedione |
| Purity: | ≥99% (HPLC) |
Highly selective and potent non-peptide NPY Y5 receptor antagonist
| Chemical Name: | N-[[trans-4-[[(4-Amino-2-quinazolinyl)amino]methyl]cyclohexyl]methyl]-1-naphthalenesulfonamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent NPY Y5 receptor antagonist
| Chemical Name: | N-[[trans-4-[(4,5-Dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]methanesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent NPY Y2 receptor antagonist
| Chemical Name: | N-[4-[(Dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide |
| Purity: | ≥98% (HPLC) |
