p53 Inhibitors: Small Molecules and Peptides
p53 is well known for its key role as a tumor suppressor protein. It is 393 amino acids (aa) in length with a predicted molecular weight of 44 kDa. It belongs to the p53 family that also includes p63 and p73. Structurally, p53 is characterized by an N-terminal transactivation domain, central DNA-binding and oligomerization domains, and a C-term...
6 results for "p53 Inhibitors Small Molecules and Peptides" in Products
6 results for "p53 Inhibitors Small Molecules and Peptides" in Products
p53 Inhibitors: Small Molecules and Peptides
p53 is well known for its key role as a tumor suppressor protein. It is 393 amino acids (aa) in length with a predicted molecular weight of 44 kDa. It belongs to the p53 family that also includes p63 and p73. Structurally, p53 is characterized by an N-terminal transactivation domain, central DNA-binding and oligomerization domains, and a C-term...
MDM2 antagonist; inhibits MDM2-p53 interaction
| Chemical Name: | (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one |
| Purity: | ≥98% (HPLC) |
p53 inhibitor. Also aryl hydrocarbon receptor agonist
| Chemical Name: | 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide |
MDM2-p53 interaction inhibitor
| Alternate Names: | NSC 652287 |
| Chemical Name: | 5,5'-(2,5-Furandiyl)bis-2-thiophenemethanol |
| Purity: | ≥97% (HPLC) |
Hdm2 inhibitor; activates p53-dependent transcription
| Chemical Name: | 5-[[3-Dimethylamino)propyl]amino]-3,10-dimethylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione dihydrochloride |
| Purity: | ≥99% (HPLC) |
Inhibitor of p53-mitochondrial binding
| Alternate Names: | NSC 303580 |
| Chemical Name: | 2-Phenylethynesulfonamide |
| Purity: | ≥99% (HPLC) |
